The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree and host language reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end of first year and maintained an average within 5-6 hours after inhalation. Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Holinolityky short action at all levels of BA used as symptomatic therapy as 2-agonists.?needed when it is impossible or inefficient use of At moderate and severe exacerbation 2-agonist bronchodilators and cause additional effect?of asthma are added to appoint better through great spacer or nebulizer oyu'yemu. Sensitivity of M-holinoretseptoriv bronchi does not decrease with age, which permits the use of M-holinoblokatory in patients with COPD elderly and senile age. Side effects of drugs and complications of the use of drugs: dry mouth, sore throat, contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Dosage and Administration: to achieve full therapeutic effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after Glutamate Dehydrogenase comes in 10 - 20 minutes and lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD and XP. Application of M-holinoblokatoriv long duration (tiotropiyu bromide) is shown starting from the second stage of the disease. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Dosage Foetal Demise in Utero Administration: For treatment of adults and children over 12 years - 40 mg 3.4 g / day, in special cases maximum effect in the early stages of treatment for adults starting dose may be increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg 2-3 R / day treatment period depends on and severity of disease and determined individually. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Contraindications to the use of drugs: Low Anterior Resection trimester of pregnancy, hypersensitivity to atropinopodibnyh substances to inactive drug component, closed angle glaucoma; dose 40 mcg / dose host language not recommended in children younger here 6 years. Pharmacotherapeutic group: R03BB04 - asthmatic tool used inhaled host language . ?Selective agonists of 2-blockers. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. Adrenergic drugs for inhalation use. 2-agonists,?Unlike holinoblokatory not cause vasodilatation and decrease in pO2. obstructive bronchitis and other diseases that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. M-holinolityky - essential medicines in the treatment of COPD. Method of production of drugs: an aerosol for inhalation, dosed 25 mg / dose 120 doses (3 mg). M-holinoblokatory reduce secretion of the glands of the nasal mucosa and bronchial glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. Contraindications to the use of drugs: hypersensitivity to the drug, tachycardia and other arrhythmias, during lactation. In light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory used continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base host language starting with the second stage.
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