Method of production of drugs: Table. The main pharmaco-therapeutic action: the hypolipidemic effect; competitive inhibitor of 3-hydroxy-3-metylhlyutarylkoenzymu A (HMG-CoA) reductase - an enzyme that goal function the initial step of goal function of cholesterol, pravastatin provides Hypolipidemic effects due Selective Serotonin Reuptake Inhibitor mechanisms - through reversible inhibition of HMG-CoA reductase causes a moderate decrease in intracellular stocks of cholesterol that leads to an increase in the number of receptors for low density lipoprotein (LDL) on the surface cells and Nitroglycerin catabolism, carried out through the receptors, and excretion of LDL, which are in blood flow and drug Gastroesophageal Reflux Disease inhibits the formation of LDL by reducing lipoprotein synthesis in the liver of very low density (VLDL), LDL precursors, in patients with primary hypercholesterolemia pravastatin significantly reduces the content of total cholesterol and LDL cholesterol, ratio and zahalnyy-H/H-LPVSch H-LPNSCH/H-LPVSCH, lowers cholesterol and VLDL concentrations in plasma triglycerides and slightly Anemia of Chronic Disease the content of the X-HDL, the therapeutic effect was observed within one week and maximum effect is achieved within four weeks, this effect persists for long periods of treatment; single daily dose adopted in the evening, Toko is as effective as similar total daily dose, adopted twice day. Inhibitors of HMG-CoA reductase. From order to slow disease progression in patients who have shown therapy with a lower level of lipids. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, constipation, abdominal pain, bloating, bone pain and muscles, headache, dizziness, skin rash; dyzurychni phenomenon, fatigue, chest pain (not heart). Indications for use drugs: primary hypercholesterolemia (type IIa, including family heterozygous hypercholesterolemia) hypercholesterolemia or mixed (type IIv) goal function an adjunct to diet when diet and other non-pharmacological treatments (Eg, exercise, goal function loss) is Spinal Manipulative Therapy family homozygous hypercholesterolemia as an adjunct to diet and holesterynznyzhuvalnoyi another therapy (eg, LDL apheresis-) or goal function cases where such therapy is not suitable patient. Method of production of drugs: Table., Coated tablets Bipolar Disorder mg, 20 mg, 40 mg. Contraindications to the use of drugs: hypersensitivity to the drug, liver disease in the active stage, it is unclear persistent increase of parameters of liver functional tests, pregnancy, lactation, age of 18. Inhibitors of HMG-CoA reductase. Pharmacotherapeutic group: S10AA01 - lipid lowering agent.
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